hrp0097p2-3 | Adrenals and HPA Axis | ESPE2023

Glucocorticoid induced adrenal insufficiency evaluated by the low dose short corticotropin test in children

Nauwynck Elise , Knauf Keanu , Anckaert Ellen , Vanbesien Jesse , Staels Willem , De Schepper Jean , Gies Inge

Background and aims: The low dose short corticotropin test (LCT) is the most frequently used test to diagnose glucocorticoid-induced adrenal insufficiency (GAI) in children. Result of the LCT must be interpreted with caution since stimulated peak cortisol (PC) thresholds depend on the assay and time of sampling. We evaluated the prevalence of GAI by the LCT using both 20 and 30 minutes sampling and cortisol measurements by the most recent Roche Elecsys Cortiso...